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The potential applications of MetaboTip are vast and varied. The spectrum of available applications is continuously growing. Some key areas where MetaboTip can have a profound impact include:
Allergies and nutritional intolerances are accompanied by systemic immune responses, which show clear metabolic signatures. Metabognostics’ allergy application detects these metabolic parameters and aids in identifying the sources of allergies or nutritional intolerances. Easy and convenient from home, without prick test and without long delays due to trial-and-error based diagnosis.
Chronic inflammation affects an increasing number of people worldwide. Diagnosis and treatment of chronic disease are often difficult because these diseases often have multiple causes. Metabognostics’ chronic inflammation application identifies inflammation-related metabolites that indicate characteristic pro- or anti-inflammatory processes.
Furthermore, the investigation of metabolic imbalances in humans is crucial for the prevention of chronic inflammatory disorders. Metabotip can detect specific substances that reflect upon individual parameters which may be relevant to chronic inflammation.
The gut microbiome is a thriving community of microorganisms—including bacteria, archaea, fungi, and viruses— in the digestive tract. This remarkable ecosystem aids in digestion, but recent scientific evidence implies a crucial role in overall health and well-being.
An imbalance in the gut microbiome—known as dysbiosis—can contribute to a range of health issues, from ulcers, irritable bowel syndrome and inflammatory bowel diseases to obesity and type 2 diabetes. The intricate connection between the gut and brain underscores the importance of nurturing a healthy microbiome for a healthy psyche.
The Impact of a Healthy Gut:
Stress, for instance, can disrupt the balance of the gut microbiome. The gut's response to stress highlights the importance of maintaining a healthy microbiome to support both physical and mental well-being. Metabognostics’ dysbiosis application identifies specific metabolic signatures that indicate dysbiosis.
Take control of your well-being today by understanding and supporting your gut microbiome—because a healthy gut means a healthier you.
Since the start of the pandemic, it has become evident that not all patients fully recover from COVID-19, leading to the emergence of a new condition known as post-acute COVID-19 syndrome (PACS) or Long COVID-19 Syndrome (LCS).
Patients suffering from Long COVID often experience persistent heterogenous symptoms like a general fatigue, lack of concentration (self-described as “brain fog”), reduced physical fitness, shortness of breath, and increased heart rate amongst others.
The severity of the initial infection does not correlate with the likelihood of developing LCS, and the underlying risk factors and comorbidities remain largely unknown. LCS resembles the chronic fatigue syndrome, which is a known phenomenon to occur secondary to viral infections. The poor understanding of LCS leads to challenges in diagnosis and treatment. This has resulted in a lack of awareness and recognition of LCS, with many cases likely going undiagnosed.
Recently, an exploratory study identified mechanisms related to energy homeostasis to be distinctly dysfunctional in LCS patients. Metabognostics’ Long COVID application established a marker signature that underscores LCS and provides metabolic parameters that doctors can use for diagnosis. The unique signatures identified with Metabotip reveal a prevalence of anti-inflammatory molecules combined with altered metabolic processes.
Metabotip, aids for more effective diagnosis, choice of a personalized treatment, and hence improved patient outcomes.
Metabotip offers a groundbreaking solution by detecting specific substances that reflect individual lifestyle factors and their potential impact on health. By analyzing individual metabolic responses to the intake of various xenobiotics—such as caffeine, nicotine, and NSAIDs—Metabotip provides a comprehensive overview of the substances we are exposed to and how our bodies uniquely respond to them. This includes identifying bioactive compounds, tracking drug metabolism, and revealing individual differences in drug effects and potential toxicity.
The technology also excels in identifying reactive oxygen species (ROS) associated metabolites, which are often missed in blood analysis. This feature is especially valuable for understanding oxidative stress and its role in chronic diseases. Additionally, Metabotip can monitor positive health effects, such as the beneficial impact of plant-derived bioactive compounds like flavonoids, which are known e.g for their protective role against carcinogenesis.
By allowing for individualized monitoring of metabolites and assessing metabolic kinetics in response to various stimuli—whether internal or external—Metabotip significantly enhances the effectiveness for personalized preventive medicine. This innovative approach empowers healthcare providers to tailor preventive strategies and interventions, ensuring a more proactive and personalized approach to maintaining and improving health.
Current methods for acute and post-mortem toxicology are expensive, time-consuming, and limited in scope. Metabognostics’ non-invasive hypoderm fluid extraction offers a convenient initial screening of drugs and drugs of abuse for forensic toxicologists. The simple sampling procedure makes it ideal for both acute and post-mortem cases, effectively identifying the presence of drugs and drugs of abuse. The detection of specific drug metabolites minimizes the risk of false-positive results, setting a new standard in forensic toxicology.